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Hélène Pelicano Selected Research

Neoplasms (Cancer)

9/2014Mitochondrial dysfunction in some triple-negative breast cancer cell lines: role of mTOR pathway and therapeutic potential.
12/2006Mitochondrial respiration defects in cancer cells cause activation of Akt survival pathway through a redox-mediated mechanism.
6/2004Stabilization of p53 is a novel mechanism for proapoptotic function of NF-kappaB.
9/2003Inhibition of mitochondrial respiration: a novel strategy to enhance drug-induced apoptosis in human leukemia cells by a reactive oxygen species-mediated mechanism.

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Hélène Pelicano Research Topics

Disease

4Neoplasms (Cancer)
09/2014 - 09/2003
2Leukemia
04/2006 - 09/2003
1Breast Neoplasms (Breast Cancer)
09/2014
1Hypoxia (Hypoxemia)
12/2006
1Acute Myeloid Leukemia (Acute Myelogenous Leukemia)
04/2006
1Mitochondrial Diseases (Mitochondrial Disease)
04/2006

Drug/Important Bio-Agent (IBA)

2Mitochondrial DNA (mtDNA)IBA
12/2006 - 09/2003
1Biological ProductsIBA
09/2014
1Small Interfering RNA (siRNA)IBA
09/2014
1NAD (NADH)IBA
12/2006
1Adenosine Triphosphate (ATP)IBA
12/2006
1fms-Like Tyrosine Kinase 3IBA
04/2006
1Phosphotransferases (Kinase)IBA
04/2006
1Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA
04/2006
1KP372-1IBA
04/2006
1Superoxides (Superoxide)IBA
06/2004
1NF-kappa B (NF-kB)IBA
06/2004
1Arsenic Trioxide (Trisenox)FDA Link
09/2003
1Reactive Oxygen Species (Oxygen Radicals)IBA
09/2003
1Antineoplastic Agents (Antineoplastics)IBA
09/2003
1Pharmaceutical PreparationsIBA
09/2003
1Free RadicalsIBA
09/2003

Therapy/Procedure

1Therapeutics
09/2014
1Drug Therapy (Chemotherapy)
04/2006